Advancing Keratoconus Treatment. The Promise of Theranostic Technology

Anna Maria Roszkowska; Marco Lombardo

doi:10.48269/MandPH-AFMKU-24-2-002

Published: 2025-07-28

Vol. 2 No. 2 (2024)

Advancing Keratoconus Treatment. The Promise of Theranostic Technology

Anna Maria Roszkowska

, Marco Lombardo

Section: review articles

https://doi.org/10.48269/MandPH-AFMKU-24-2-002

Abstract

Background:
Keratoconus, a progressive ectatic disorder of the cornea, presents significant challenges in clinical management due to its unpredictable progression and individualized nature. Advances in treatment modalities, particularly corneal cross-linking (CXL), have revolutionized the ability to halt disease progression. Yet, a significant gap remains in achieving personalized, outcome-driven interventions.

Material and methods:
Literature review

Results:
New personalized CXL approach based on theranostic biomarkers proved safe and effective in the treatment of KC and offers personalized approach to treat the disease.

Conclusions:
Theranostics technology integrated with advanced UV-A device for CXL procedure permits to deliver the precise therapeutical dose of riboflavin and personalized UV-A light amount for the photo-activation in the cornea. This real-time monitoring of riboflavin concentration in the cornea during CXL procedure permits to obtain better predictability of the final outcome on personal basis.

Keywords:

corneal cross-linking , keratoconus , theranostic

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Roszkowska, Anna Maria, and Marco Lombardo. “Advancing Keratoconus Treatment. The Promise of Theranostic Technology”. Medicine and Public Health, vol. 2, no. 2, July 2025, pp. 1–8, doi:10.48269/MandPH-AFMKU-24-2-002.

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Vol. 2 No. 2 (2024)
Published: 2025-09-09

eISSN: 2956-9443

Publisher

AFM Publishing House of the Andrzej Frycz Modrzewski Krakow University

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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